Manchester United manager has named Scott McTominay and Brandon Williams in his team to face Brighton in the Premier League.
There were doubts over the former’s availability but he has been passed fit to start the match at Old Trafford.
Ole Gunnar Solskjaer, meanwhile, has handed Williams his first Premier League start as he comes in for Ashley Young at left-back.
The 19-year-old is the only change to the team which lost 1-0 to Bournemouth last weekend.
Brighton have also opted not to change too much, sticking with a back-four and only making two personnel alterations.
Lewis Dunk comes in for Adam Webster, while Leandro Trossard replaces Pascal Gross in the first XI.
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Manchester United: De Gea, Wan Bissaka, Lindelof, Maguire, Williams, McTominay, Fred, James, Andreas Pereira, Rashford, Martial.
Substitute: Jones, Mata, Lingard, Rojo, Romero, Greenwood, Garner.
Brighton: Ryan, Montoya, Dunk, Duffy, Burn, Propper, Stephens, Alzate, Trossard, Maupay, Connolly.
Substitute: Gross, Balogun, Murray, Mooy, March, Schelotto, Button.
Referee: Jonathan Moss (County Durham)