Southampton welcome Manchester United to St Mary’s on Saturday afternoon in a fixture which promises entertainment.
The game will be live on talkSPORT as the first of three exclusively live fixtures on Saturday as we bring you yet another GameDay.
United rescued a point in the same fixture last season, with the Saints going 2-0 up before collapsing.
It proved to be Mark Hughes’ last game in charge, with former Red Devils manager Jose Mourinho also getting the sack shortly after.
Ralph Hasenhuttl and Ole Gunnar Solskjaer will now pit their wits against one another after pikcing up contrasting results last week.
The Saints picked up their first win of the season by beating 10-man Brighton, while Man United were beaten in a shock upset at Old Trafford as Crystal Palace picked up a 2-1 win.
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Hasenhuttl may find it difficult to build on the impressive win at the Amex last weekend after his squad picked up a number of injuries.
Nathan Redmond is set to miss at least two weeks after injuring his ankle during the Carabao Cup win over Fulham in midweek.
Captain Ryan Bertrand has returned to training but is not fit enough to start, while Michael Obefemi is also likely to miss the visit of the Red Devils because of cramp.
Anthony Martial and Luke Shaw are missing for the visitors, meaning the left hand side of the team will need restructuring.
Shaw picked up a hamstring injury, while Martial was also injured during the Palace defeat and picked up a thigh problem.
Mason Greenwood could well start on the flanks with Daniel James, but defensive trio Timothy Fosu-Mensah, Diogo Dalot and Eric Bailly remain out.
LIVE on talkSPORT
Check out all the live commentaries coming up across the talkSPORT network this week
- Cardiff vs Fulham (Friday, 7:45pm) – talkSPORT 2
- Southampton vs Manchester United (Saturday, 12:30pm) – talkSPORT
- Bristol City vs Middlesbrough (Saturday, 3pm) – talkSPORT 2
- Chelsea vs Sheffield United (Saturday, 3pm) – talkSPORT 2
- Burnley vs Liverpool (Saturday, 5:30pm) – talkSPORT
Saturday is GameDay on talkSPORT and talkSPORT 2 as we become your go to destination for all the Premier League action.
We’ll bring you LIVE commentary of Premier League games across all three time slots on Saturday – 12.30pm, 3pm and 5.30pm – delivering award-winning coverage to more GameDay listeners than ever.