Heung-Min Son will miss up to four games for Tottenham Hotspur after he was called up to the South Korea squad for the AFC Asian Cup in January 2019.
The tournament takes place between January 5 and February 1 in the United Arab Emirates with 24 nations taking part.
Son will miss the first part of the tournament but will join up with the rest of the South Korea squad for their final group match against China.
The Spurs forward will be available for the Manchester United match on Sunday, January 13, but will then leave for the UAE.
He will miss Premier League games against Fulham and Watford and also the second leg of the Carabao Cup semi-final against Chelsea.
Son scored in the quarter-final victory over Arsenal to help them through to the final four.
If South Korea progress to the final of the competition, then he would also miss the match with Newcastle on Saturday, February 2.
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South Korea have been drawn in group C of the competition alongside China, Philippines and Kyrgyz Republic.
Earlier this year, Son secured an exemption from military service in South Korea, along with his teammates, when they beat Japan to win gold at the Asian Games football tournament.